Hundreds of lawyers and their supporters boarded buses in Karachi that will carry them to the capital, Islamabad, where they will demand that the government immediately restore judges that the previous president ousted.
The demonstrators want President Asif Ali Zardari to fulfill a pledge to reinstate all judges sacked under former President Pervez Musharraf. According to the government the march is aimed at destabilizing the country.
Police say they have arrested more than 400 opposition activists in the past few days.
The authorities have also banned political gatherings across the country, saying they could trigger bloodshed.
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